SCHEMBL404069

SCHEMBL404069

Clc1ccc2nc(Cl)c(Cl)nc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.55
PIK3CG P48736 2/20 0.54
ALDH1A1 P00352 2/20 0.52
MAPT P10636 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
USP2 O75604 1/20 0.52
KMT2A Q03164 1/20 0.52
HSD17B10 Q99714 1/20 0.52
F7 P08709 1/20 0.50
F3 P13726 1/20 0.50
DYRK1A Q13627 1/20 0.50
PIK3R1 P27986 1/20 0.50
PIK3CA P42336 1/20 0.50
NR4A2 P43354 1/20 0.45
CUL4A Q13619 1/20 0.43
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
THRB P10828 1/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29581162 1.00 TDP1 (0.55) TDP1PIK3CGALDH1A1MAPTKDM4E
SCHEMBL5157381 0.89 PIK3CG (0.58) TDP1PIK3CGALDH1A1MAPTKDM4E
SCHEMBL11597356 0.85 PIK3CG (0.43) TDP1PIK3CGALDH1A1MAPTKDM4E
SCHEMBL1138685 0.84 PIK3CG (0.55) PIK3CGALDH1A1MAPTKDM4EMEN1
SCHEMBL6303670 0.84 KMT2A (0.62) TDP1PIK3CGALDH1A1MAPTKDM4E
SCHEMBL6311061 0.84 KMT2A (0.62) TDP1PIK3CGALDH1A1MAPTKDM4E
SCHEMBL28162186 0.84 PIK3CG (0.46) TDP1PIK3CGALDH1A1MAPTKDM4E
SCHEMBL17269519 0.84 PIK3CG (0.54) PIK3CGALDH1A1MAPTKDM4EMEN1
SCHEMBL15196672 0.84 PIK3CG (0.54) PIK3CGALDH1A1MAPTKDM4EMEN1
SCHEMBL29856205 0.82 NQO2 (0.56) TDP1PIK3CGALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117110470-A Method for detecting content of impurity 2,3, 6-trichloroquinoxaline in 2, 6-dichloro quinoxaline 山东京博生物科技有限公司 2023-11-24 CN claimed
US-4119460-A FUSED CARBOCYCLIC RING COMPOUNDS, POLYPHENYL COMPOUNDS NITROGEN-FREE POLYARYLATED COMPOUNDS EASTMAN KODAK COMPANY (US) 1978-10-10 US claimed
EP-4598535-A2 INHIBITORS OF SPNS2 AND USES THEREOF New York University (US) 2025-08-13 EP disclosed
WO-2025021868-A1 TRAF2 INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER DISEASES Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) 2025-01-30 WO disclosed
WO-2024076610-A2 INHIBITORS OF SPNS2 AND USES THEREOF NEW YORK UNIVERSITY (US) 2024-04-11 WO disclosed
CN-117110470-A Method for detecting content of impurity 2,3, 6-trichloroquinoxaline in 2, 6-dichloro quinoxaline 山东京博生物科技有限公司 2023-11-24 CN disclosed
CN-117110470-A Method for detecting content of impurity 2,3, 6-trichloroquinoxaline in 2, 6-dichloro quinoxaline 山东京博生物科技有限公司 2023-11-24 CN disclosed
CN-117110470-A Method for detecting content of impurity 2,3, 6-trichloroquinoxaline in 2, 6-dichloro quinoxaline 山东京博生物科技有限公司 2023-11-24 CN disclosed
CN-111454223-B Synthetic method of 2, 3-dihydroxy-6-chloroquinoxaline 山东京博生物科技有限公司 2022-05-24 CN disclosed
US-11121326-B2 Organic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2021-09-14 US disclosed
US-11121326-B2 Organic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2021-09-14 US disclosed
US-4201583-A DRY PROCESS, NONSILVER PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4201591-A Electrically activated recording material and process EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4200748-A ANXIOLYTIC AGENTS AMERICAN CYANAMID COMPANY (US) 1980-04-29 US disclosed
US-4195990-A PARA-LINKED POLYPHENYLS OR POLYARYL UNSATURATED COMPOUNDS EASTMAN KODAK COMPANY (US) 1980-04-01 US disclosed
US-4160666-A Polymeric chemical sensitizers for organic photoconductive compositions EASTMAN KODAK COMPANY (US) 1979-07-10 US disclosed
US-4145214-A P-TERPHENYL AND P-QUATERPHENYL, ELECTROPHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1979-03-20 US disclosed
US-4119460-A FUSED CARBOCYCLIC RING COMPOUNDS, POLYPHENYL COMPOUNDS NITROGEN-FREE POLYARYLATED COMPOUNDS EASTMAN KODAK COMPANY (US) 1978-10-10 US disclosed
US-4025510-A DYES FOR POLYESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-05-24 US disclosed
US-3935312-A Combating fungi with imidazo-[4,5-b]quinoxalines BAYER AKTIENGESELLSCHAFT (DT) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11121326-B2 Organic compound, light-emitting element, light-emitting device, electronic device and lighting device AOX1, RECQL, NFE2L2 TDP1 3413/4885PIK3CG 4264/4885ALDH1A1 604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.