Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27914024 | 0.86 | KEAP1 (0.54) | LMNAALDH1A1TDP1HPGDHDAC1 | |
| SCHEMBL11597575 | 0.84 | TDP1 (0.43) | LMNAALDH1A1SMN1; SMN2NPSR1TDP1 | |
| SCHEMBL17320255 | 0.82 | TGM2 (0.52) | LMNAALDH1A1TDP1HPGDHDAC1 | |
| SCHEMBL14812493 | 0.77 | CYP2C19 (0.46) | LMNAALDH1A1TDP1HPGDHDAC1 | |
| SCHEMBL23898774 | 0.76 | TGM2 (0.46) | LMNAALDH1A1TDP1HPGDKEAP1 | |
| SCHEMBL5527681 | 0.76 | TDP1 (0.63) | LMNAALDH1A1TDP1HPGDHDAC1 | |
| SCHEMBL28207649 | 0.76 | TDP1 (0.63) | LMNAALDH1A1TDP1HPGDHDAC1 | |
| SCHEMBL4415392 | 0.76 | TDP1 (0.63) | LMNAALDH1A1TDP1HPGDHDAC1 | |
| SCHEMBL14456718 | 0.75 | LMNA (0.49) | LMNAALDH1A1SMN1; SMN2NPSR1TDP1 | |
| SCHEMBL17310391 | 0.75 | CYP2C19 (0.53) | LMNAALDH1A1NPSR1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088631-A | N-(1-METHYL-3-ARYL-3-OXOPROPYL) ALKYLAMIDES AS ANTIOXIDANTS AND THERMO- AND UV STABILIZERS | THE GOODYEAR TIRE AND RUBBER COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4048227-A | LIGHT STABILIZER, COPOLYMERIZING MONOMER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-09-13 | — | — | US | disclosed |