Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23898774 | 0.89 | TGM2 (0.46) | TGM2CYP2C19LMNAHPGDTSHR | |
| SCHEMBL14812493 | 0.86 | CYP2C19 (0.46) | TGM2CYP2C19LMNAHPGDTSHR | |
| SCHEMBL27914024 | 0.86 | KEAP1 (0.54) | TGM2CYP2C19LMNAHPGDTSHR | |
| SCHEMBL345815 | 0.84 | TGM2 (0.52) | TGM2CYP2C19LMNAHPGDTSHR | |
| SCHEMBL3903507 | 0.84 | CYP2C19 (0.68) | TGM2CYP2C19TSHRAKT1ALDH1A1 | |
| SCHEMBL11597575 | 0.84 | TDP1 (0.43) | TGM2CYP2C19LMNAHPGDAKT1 | |
| SCHEMBL701472 | 0.82 | TGM2 (0.50) | TGM2CYP2C19LMNAHPGDTSHR | |
| SCHEMBL11596335 | 0.82 | LMNA (0.48) | TGM2CYP2C19LMNAHPGDTSHR | |
| SCHEMBL7745702 | 0.81 | CYP2C19 (0.49) | TGM2CYP2C19LMNATSHRALDH1A1 | |
| SCHEMBL4415392 | 0.81 | TDP1 (0.63) | LMNAHPGDTSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497026-B1 | POLYMERIC COMPOSITE CHIRAL STATIONARY PHASES OF BRUSH TYPE | UNIV ROMA (IT) | 2015-12-09 | — | — | EP | disclosed |