Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11596475 | 0.88 | ADRB2 (0.50) | ADRB2HIF1ACYP2D6TSHRCYP1A2 | |
| SCHEMBL8077438 | 0.83 | FOLH1 (0.51) | ADRB2HIF1ATSHRADRB1LMNA | |
| SCHEMBL8067713 | 0.82 | ADRB2 (0.62) | ADRB2HIF1ACYP2D6TSHRCYP1A2 | |
| SCHEMBL11596481 | 0.81 | ADRB2 (0.47) | ADRB2HIF1ACYP2D6TSHRCYP1A2 | |
| SCHEMBL12210726 | 0.78 | SLC22A3 (0.68) | ADRB2HIF1ACYP2D6TSHRCYP1A2 | |
| SCHEMBL2585166 | 0.77 | ADRB2 (0.59) | ADRB2HIF1ACYP2D6TSHRCYP1A2 | |
| SCHEMBL14134261 | 0.77 | ADRB2 (0.49) | ADRB2HIF1ACYP2D6TSHRCYP1A2 | |
| SCHEMBL14134262 | 0.77 | ADRB2 (0.49) | ADRB2HIF1ACYP2D6TSHRCYP1A2 | |
| SCHEMBL4670569 | 0.77 | ADRB2 (0.48) | ADRB2ADRB1LMNAKMT2AALDH1A1 | |
| SCHEMBL14080487 | 0.77 | ADRB2 (0.48) | ADRB2ADRB1LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101579-A | Phenethanolamine ethers | ALLEN & HANBURYS LIMITED (GB) | 1978-07-18 | — | — | US | disclosed |