Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228986 | 0.83 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2HDAC6MEN1 | |
| SCHEMBL1095490 | 0.83 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2HDAC6HDAC3 | |
| SCHEMBL22479064 | 0.81 | TUBB4A (0.54) | NPC1RAB9ATUBB4ATUBBTUBA3C | |
| SCHEMBL24124671 | 0.81 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2MEN1MAPT | |
| SCHEMBL11583452 | 0.80 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2HDAC6HDAC3 | |
| SCHEMBL11222774 | 0.78 | DYRK1A (0.58) | NPC1RAB9ASMN1; SMN2HSD17B1HSD17B2 | |
| SCHEMBL193533 | 0.77 | ALDH1A1 (0.62) | NPC1RAB9ASMN1; SMN2HSD17B1HSD17B2 | |
| Hydrochloric Acid SCHEMBL11596610 | 0.76 | RAB9A (0.68) | NPC1RAB9ASMN1; SMN2HDAC6HDAC3 | |
| SCHEMBL11229253 | 0.75 | SMN1; SMN2 (0.39) | NPC1RAB9ASMN1; SMN2HDAC6HSD17B1 | |
| SCHEMBL11227721 | 0.74 | GAA (0.53) | NPC1RAB9ASMN1; SMN2HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118232-A | Photographic material containing sulphonic acid group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1978-10-03 | — | — | US | disclosed |
| US-4051123-A | Sulfonic-acid-group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1977-09-27 | — | — | US | disclosed |