Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4072639 | 0.84 | KDM4E (0.41) | SMN1; SMN2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL11227721 | 0.80 | GAA (0.53) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL11228986 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL11596604 | 0.75 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL11222712 | 0.75 | HSD17B1 (0.41) | SMN1; SMN2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL2479649 | 0.74 | RAB9A (0.54) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL22479064 | 0.74 | TUBB4A (0.54) | NPC1RAB9AGAAAKR1B1PPARA | |
| SCHEMBL11224458 | 0.74 | DYRK1A (0.55) | SMN1; SMN2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL11335739 | 0.73 | KDM4E (0.65) | SMN1; SMN2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL11171869 | 0.72 | ALDH1A1 (0.34) | SMN1; SMN2NPC1RAB9AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326065-A | PLASTICS, VARNISHES, POLYESTERS | EASTMAN KODAK COMPANY (US) | 1982-04-20 | — | — | US | disclosed |
| US-4251433-A | BENZOTRIAZOLE DERIVATIVES; FOR POLYMERS | EASTMAN KODAK COMPANY (US) | 1981-02-17 | — | — | US | disclosed |
| US-4236013-A | ADDITIVES FOR POLYMERS | EASTMAN KODAK COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4137235-A | ULTRAVIOLET STABILIZERS IN POLYMERIC COMPOSITIONS | EASTMAN KODAK COMPANY (US) | 1979-01-30 | — | — | US | disclosed |
| US-4116928-A | Heterocylic ester, ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1978-09-26 | — | — | US | disclosed |