Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11597018 | 1.00 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1TP53LMNAMAPT | |
| SCHEMBL11595489 | 0.82 | L3MBTL1 (0.57) | ALDH1A1L3MBTL1TP53LMNAMAPT | |
| SCHEMBL11596464 | 0.82 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1TP53LMNAMAPT | |
| SCHEMBL11595226 | 0.82 | L3MBTL1 (0.57) | ALDH1A1L3MBTL1TP53LMNAMAPT | |
| SCHEMBL11596614 | 0.82 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1TP53LMNAMAPT | |
| SCHEMBL11726581 | 0.81 | KMT2A (0.63) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11597707 | 0.79 | GSTO1 (0.47) | ALDH1A1L3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL11595563 | 0.79 | CNR2 (0.54) | ALDH1A1L3MBTL1TP53LMNAMAPT | |
| SCHEMBL11595283 | 0.79 | CNR2 (0.54) | ALDH1A1L3MBTL1TP53LMNAMAPT | |
| SCHEMBL11527071 | 0.78 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1TP53LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125614-A | DIURETIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |