Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.44 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11596502 | 0.84 | AKR1C3 (0.62) | PRMT1F10PRSS1PRSS2PRSS3 | |
| SCHEMBL11597544 | 0.83 | PRMT1 (0.56) | PRMT1F10PRSS1PRSS2PRSS3 | |
| SCHEMBL11598345 | 0.82 | GAA (0.44) | F10PRSS1PRSS2PRSS3HTT | |
| SCHEMBL11595997 | 0.82 | PRMT1 (0.55) | PRMT1F10PRSS1PRSS2PRSS3 | |
| SCHEMBL11597183 | 0.81 | LMNA (0.51) | LMNASLC12A2SLC12A5GLAMAPT | |
| SCHEMBL11528278 | 0.80 | PRMT1 (0.53) | PRMT1F10PRSS1PRSS2PRSS3 | |
| SCHEMBL11384157 | 0.79 | MAPT (0.52) | PRMT1F10PRSS1PRSS2PRSS3 | |
| SCHEMBL11597707 | 0.78 | GSTO1 (0.47) | HTTMAPTALDH1A1POLBTDP1 | |
| SCHEMBL11598316 | 0.76 | ALDH1A1 (0.48) | HTTLMNAMAPTALDH1A1POLB | |
| SCHEMBL940417 | 0.75 | ALDH1A1 (0.62) | PRMT1F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125614-A | DIURETIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
| US-4061761-A | Thiazolidine derivatives | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |