Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.57 |
| ▸ | RXRB | P28702 | 3/20 | 0.57 |
| ▸ | RXRG | P48443 | 2/20 | 0.57 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | POLQ | O75417 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30120956 | 1.00 | RXRA (0.57) | RXRARXRBRXRGAGBL2PSEN1 | |
| SCHEMBL17899450 | 0.88 | RXRA (0.72) | RXRARXRBRXRGAGBL2PSEN1 | |
| SCHEMBL11599008 | 0.84 | RXRA (0.56) | RXRARXRBRXRGNR1H4 | |
| SCHEMBL24651096 | 0.81 | POLB (0.45) | PPARGPPARDPPARA | |
| SCHEMBL30120834 | 0.81 | IDO1 (0.51) | RXRARXRBRXRGAGBL2PSEN1 | |
| SCHEMBL7999435 | 0.81 | RXRA (0.48) | RXRARXRBRXRGAGBL2PSEN1 | |
| SCHEMBL5574328 | 0.81 | CES2 (0.53) | RXRARXRBRXRGAGBL2PSEN1 | |
| SCHEMBL892902 | 0.81 | IDO1 (0.51) | RXRARXRBRXRGAGBL2PSEN1 | |
| SCHEMBL1060068 | 0.80 | RXRA (0.46) | RXRARXRBRXRGPSEN1PSEN2 | |
| SCHEMBL11068250 | 0.80 | RXRA (0.51) | RXRARXRBRXRGAGBL2PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240382488-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. | 2024-11-21 | — | — | US | disclosed |
| WO-2022212326-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-06 | — | — | WO | disclosed |
| WO-2022212326-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-06 | — | — | WO | disclosed |
| US-10392367-B2 | IRE1 small molecule inhibitors | QUENTIS THERAPEUTICS, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-10392367-B2 | IRE1 small molecule inhibitors | QUENTIS THERAPEUTICS, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| WO-2018222917-A1 | IRE1 SMALL MOLECULE INHIBITORS | QUENTIS THERAPEUTICS, INC. (US) | 2018-12-06 | — | — | WO | disclosed |
| US-20180346447-A1 | IRE1 SMALL MOLECULE INHIBITORS | CORNELL UNIVERSITY | 2018-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240382488-A1 | NEK7 INHIBITORS | NEK7, NEK11, NEK2 | RXRA 2874/4885RXRB 3018/4885RXRG 2180/4885 |
| US-10392367-B2 | IRE1 small molecule inhibitors | XBP1, ERN2, ERN1 | RXRA 3385/4885RXRB 3360/4885RXRG 3247/4885 |
| US-20180346447-A1 | IRE1 SMALL MOLECULE INHIBITORS | XBP1, ERN2, ERN1 | RXRA 3385/4885RXRB 3360/4885RXRG 3247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.