Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.47 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599076 | 1.00 | LMNA (0.49) | LMNASMN1; SMN2TPSAB1TPSD1TPSG1 | |
| SCHEMBL21416177 | 0.85 | HTT (0.51) | LMNASMN1; SMN2TPSAB1TPSD1TPSG1 | |
| SCHEMBL25675422 | 0.85 | HTT (0.51) | LMNASMN1; SMN2TPSAB1TPSD1TPSG1 | |
| SCHEMBL1171418 | 0.83 | LMNA (0.56) | LMNASMN1; SMN2TPSAB1TPSD1TPSG1 | |
| SCHEMBL10081124 | 0.83 | LMNA (0.63) | LMNASMN1; SMN2TPSAB1TPSD1TPSG1 | |
| SCHEMBL7940762 | 0.82 | TGM2 (0.54) | LMNASMN1; SMN2TPSAB1TPSD1TPSG1 | |
| SCHEMBL4073528 | 0.80 | TPSAB1 (0.53) | LMNASMN1; SMN2TPSAB1TPSD1TPSG1 | |
| SCHEMBL2065470 | 0.80 | SMN1; SMN2 (0.59) | LMNASMN1; SMN2TPSAB1TPSD1TPSG1 | |
| SCHEMBL10641387 | 0.78 | LMNA (0.61) | LMNASMN1; SMN2TPSAB1TPSD1TPSG1 | |
| SCHEMBL11414856 | 0.78 | LMNA (0.54) | LMNASMN1; SMN2TPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111933-A | PROTECTION OF FUNCTIONAL GROUPS DURING REACTION AND THEIR SUBSEQUENT RESTORATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | disclosed |