Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.50 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.50 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10081124 | 0.86 | LMNA (0.63) | LMNASMN1; SMN2HTTTPSAB1TPSD1 | |
| SCHEMBL25675422 | 0.83 | HTT (0.51) | TGM2LMNASMN1; SMN2HTTTPSAB1 | |
| SCHEMBL21416177 | 0.83 | HTT (0.51) | TGM2LMNASMN1; SMN2HTTTPSAB1 | |
| SCHEMBL17895893 | 0.83 | ALDH1A1 (0.56) | TGM2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11599076 | 0.82 | LMNA (0.49) | TGM2LMNASMN1; SMN2HTTTPSAB1 | |
| SCHEMBL11599079 | 0.82 | LMNA (0.49) | TGM2LMNASMN1; SMN2HTTTPSAB1 | |
| SCHEMBL10641387 | 0.82 | LMNA (0.61) | TGM2LMNASMN1; SMN2HTTTPSAB1 | |
| SCHEMBL3231538 | 0.81 | PPID (0.64) | LMNASMN1; SMN2HTTTPSAB1TPSD1 | |
| SCHEMBL2341872 | 0.81 | TGM2 (0.62) | TGM2LMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL1171418 | 0.81 | LMNA (0.56) | TGM2LMNASMN1; SMN2HTTTPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245938-B1 | COMPOUND SUITABLE FOR USE BOTH AS DERIVATIZING GROUP FOR OPTICAL SEPARATION OF ENANTIOMERS AND AS PROTECTING GROUP FOR PREPARATION OF MISACYLATED TRNA | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2001-06-12 | — | — | US | disclosed |
| US-4970297-A | CONTAINING ISOXAZOLE RING | SYNTEX (U.S.A.) INC. (US) | 1990-11-13 | — | — | US | disclosed |