Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL846835 | 0.83 | GSK3B (0.64) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL600578 | 0.83 | RAB9A (0.83) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL8237426 | 0.82 | KMT2A (0.62) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL11599481 | 0.80 | GSK3B (0.70) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL11765652 | 0.79 | ALDH1A1 (0.68) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL11135945 | 0.77 | KMT2A (0.56) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL839126 | 0.77 | KMT2A (0.72) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL20853597 | 0.77 | NPC1 (0.67) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL4842224 | 0.77 | NPC1 (0.73) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL3035986 | 0.77 | NPC1 (0.67) | RAB9ANPC1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082807-A | REACTING AN AROMATIC COMPOUND WITH AN ACETOACETYL FLUORIDE; HYDROGEN FLUORIDE | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-04 | — | — | US | disclosed |
| US-3937737-A | CHEMICAL INTERMEDIATES, DYES, PLASTICS, METAL COMPLEXES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-10 | — | — | US | disclosed |