Sugi Predict

Sugi Predict / Compounds / SCHEMBL846835

SCHEMBL846835

SCHEMBL846835

Cc1ccc(C(=O)CCl)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GSK3B P49841 3/20 0.64
▸ ALDH1A1 P00352 10/20 0.60
▸ HIF1A Q16665 2/20 0.60
▸ TRPA1 O75762 1/20 0.60
▸ MAPK1 P28482 1/20 0.60
▸ RAB9A P51151 4/20 0.57
▸ NPC1 O15118 3/20 0.57
▸ KMT2A Q03164 3/20 0.57
▸ MEN1 O00255 2/20 0.57
▸ TP53 P04637 1/20 0.57
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ CES2 O00748 2/20 0.54
▸ CES1 P23141 2/20 0.54
▸ LMNA P02545 2/20 0.54
▸ MAPT P10636 4/20 0.53
▸ POLB P06746 2/20 0.53
▸ SMN1; SMN2 Q16637 3/20 0.52
▸ THRA P10827 1/20 0.52
▸ THRB P10828 1/20 0.52
▸ HPGD P15428 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11480265 0.87 GSK3B (0.80) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL3890776 0.87 GAA (0.57) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL12064834 0.87 THRA (0.73) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL8386470 0.85 GSK3B (0.48) GSK3BALDH1A1HIF1ATRPA1MAPK1
Phenacyl Chloride SCHEMBL28106866 0.84 GSK3B (0.70) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL11599418 0.83 RAB9A (0.60) GSK3BALDH1A1HIF1ARAB9ANPC1
SCHEMBL25029731 0.82 GSK3B (0.59) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL2337097 0.82 KMT2A (0.64) GSK3BALDH1A1RAB9ANPC1KMT2A
SCHEMBL28360954 0.81 GSK3B (0.64) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL28030140 0.81 GSK3B (0.64) GSK3BALDH1A1HIF1ATRPA1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350143-A Preparation method of a-chloro-p-methylacetophenone 辽宁鑫义源锦新材料股份有限公司 2025-01-24 — — CN claimed
CN-109400534-A A kind of production improvement technique of 1- hydroxyl -4- (4 '-aminomethyl phenyl) -2- first oxime imidazoles -3- oxide 兰博尔开封科技有限公司 2019-03-01 — — CN claimed
CN-102424671-B Synthesis method of 4-chloro-2-cyano-1-dimethylamino-sulfonyl-5-(4-methylphenyl)imidazo XIAN MODERN CHEMISTRY RES INST 2014-05-14 — — CN claimed
CN-102424671-A Synthesis method of 4-chloro-2-cyano-1-dimethylaminosulfonyl-5- (4-methylphenyl) imidazole XIAN MODERN CHEMISTRY RES INST 2012-04-25 — — CN claimed
US-20110288315-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE COMPOUND DAISO CO., LTD. (JP) 2011-11-24 — — US claimed
EP-2325178-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE COMPOUND DAISO CO., LTD. (JP) 2011-05-25 — — EP claimed
CN-101336242-A Improved method of preparation for imidazolepyridines MALLINCKRODT INC (US) 2008-12-31 — — CN claimed
US-20080293947-A1 Method of Preparation for Imidazolepyridines MALLINCKRODT INC. 2008-11-27 — — US claimed
EP-1966201-A1 IMPROVED METHOD OF PREPARATION FOR IMIDAZOLEPYRIDINES Mallinckrodt, Inc. (US) 2008-09-10 — — EP claimed
WO-2007064444-A1 IMPROVED METHOD OF PREPARATION FOR IMIDAZOLEPYRIDINES MALLINCKRODT INC. (US) 2007-06-07 — — WO claimed
US-4665246-A Method of producing ethynyl aromatic compounds CHEM BIOCHEM RESEARCH, INC. (US) 1987-05-12 — — US claimed
JP-9012538-A — — None — — JP disclosed
JP-54112830-A — — None — — JP disclosed
CN-122061171-A Preparation process for co-production of organic halide by electrolysis hydrogen production based on seawater resource utilization 崂山国家实验室 2026-05-19 — — CN disclosed
CN-122059895-A Preparation method of 1,2, 4-triazine derivative 江西同和药业股份有限公司 2026-05-19 — — CN disclosed
JP-S54112830-A PREPARATION OF 4-2-(4-METHYLPHENYL)ETHOXYANILINE AND ITS PREPARATION SUMITOMO CHEM CO LTD 1979-09-04 — — JP disclosed
US-4153606-A Process for the production of thiazoline-(3) compounds DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1979-05-08 — — US disclosed
US-3993645-A Stilbene optical brighteners and compositions brightened therewith STERLING DRUG INC. (US) 1976-11-23 — — US disclosed
US-3974144-A BENZOFURAN, BENZOTHIOPHENE, NAPHTHOFURAN, OPTICAL BRIGHTENER STERLING DRUG INC. (US) 1976-08-10 — — US disclosed
US-3932301-A NYLON, POLYESTERS STERLING DRUG INC. (US) 1976-01-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288315-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE COMPOUND CYP51A1, KMO, TALDO1 GSK3B 776/4885ALDH1A1 453/4885HIF1A 1833/4885
US-20080293947-A1 Method of Preparation for Imidazolepyridines ITPA, QDPR, NISCH GSK3B 4451/4885ALDH1A1 841/4885HIF1A 2968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.