Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.55 |
| ▸ | CTSK | P43235 | 6/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CTSB | P07858 | 2/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | REN | P00797 | 2/20 | 0.50 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048302 | 0.89 | REN (0.62) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL8526673 | 0.89 | REN (0.62) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL7295855 | 0.89 | CTSS (0.69) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL5050550 | 0.89 | CTSS (0.69) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL7295862 | 0.89 | CTSS (0.69) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL1323164 | 0.85 | NAALAD2 (0.66) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL8684458 | 0.85 | NAALAD2 (0.66) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL20836770 | 0.85 | NAALAD2 (0.66) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL9439238 | 0.85 | NAALAD2 (0.66) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL3922795 | 0.84 | CTSS (0.60) | CTSSCTSKCTSLCTSBACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4089821-A | Synthesis of peptide amides | ARMOUR PHARMACEUTICAL COMPANY (US) | 1978-05-16 | — | — | US | disclosed |