Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.60 |
| ▸ | CTSK | P43235 | 8/20 | 0.60 |
| ▸ | CTSB | P07858 | 4/20 | 0.60 |
| ▸ | CTSL | P07711 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6292769 | 1.00 | CTSS (0.60) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL2402235 | 1.00 | CTSS (0.60) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL5050550 | 0.90 | CTSS (0.69) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL7295855 | 0.90 | CTSS (0.69) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL7295862 | 0.90 | CTSS (0.69) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL11567443 | 0.89 | PTPN1 (0.57) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL11210637 | 0.88 | CTSS (0.54) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL11199973 | 0.88 | CTSS (0.54) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL17865714 | 0.87 | CTSS (0.58) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL7151519 | 0.87 | CTSS (0.59) | CTSSCTSKCTSBCTSLATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047690-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 2000-11-02 | — | — | EP | claimed |
| WO-1999032480-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1999-07-01 | — | — | WO | claimed |
| US-5821331-A | INHIBIT THE PROTEOLYTIC ACTIVITY OF PROTEASES | ELI LILLY AND COMPANY (US) | 1998-10-13 | — | — | US | claimed |
| EP-0632051-A1 | Anti-picornaviral agents | ELI LILLY AND COMPANY (US) | 1995-01-04 | — | — | EP | claimed |
| CN-115477685-A | Application of selenium-containing polypeptide compound in preparation of antibacterial drugs | 浙江工业大学 | 2022-12-16 | — | — | CN | disclosed |
| CN-109715605-B | Process for preparing carotenoid monoesters | 巴斯夫欧洲公司 | 2022-04-12 | — | — | CN | disclosed |
| WO-2018050793-A1 | PROCESS FOR PREPARING PHOSPHONIUM SALT ESTERS AS BUILDING BLOCKS FOR CAROTENOIDES | BASF SE (DE) | 2018-03-22 | — | — | WO | disclosed |
| WO-2018050792-A1 | PROCESS FOR PREPARING ESTERS OF 12'-APOCAROTENALS AS BUILDING BLOCKS FOR CAROTENOIDS | BASF SE (DE) | 2018-03-22 | — | — | WO | disclosed |
| WO-2018050794-A1 | PROCESS FOR PREPARING OF CAROTENOID MONO-ESTERS | BASF SE (DE) | 2018-03-22 | — | — | WO | disclosed |
| WO-2018050795-A1 | PROCESS FOR PREPARING OF CAROTENOID MONO-ESTERS | BASF SE (DE) | 2018-03-22 | — | — | WO | disclosed |
| US-8076285-B2 | Lysobactin amides | AICURIS GMBH & CO. KG (DE) | 2011-12-13 | — | — | US | disclosed |
| US-20090203582-A1 | LYSOBACTIN AMIDES | BAYER HEALTHCARE AG (DE) | 2009-08-13 | — | — | US | disclosed |
| US-4591648-A | Histidine protection | NATIONAL RESEARCH DEVELOPMENT CORP. (GB) | 1986-05-27 | — | — | US | disclosed |
| EP-0061933-B1 | HISTIDINE PROTECTION | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-03-27 | — | — | EP | disclosed |
| EP-0017536-B1 | PROCESS FOR THE PREPARATION OF SOMATOSTATINE | SANOFI S.A. (FR) | 1983-03-23 | — | — | EP | disclosed |
| EP-0061933-A2 | Histidine protection | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1982-10-06 | — | — | EP | disclosed |
| US-4337194-A | MULTISTEP, WITH PURIFICATION BY WASHING AFTER EACH COUPLING | C. M. INDUSTRIES (FR) | 1982-06-29 | — | — | US | disclosed |
| EP-0017536-A2 | Process for the preparation of somatostatine | SANOFI S.A. (FR) | 1980-10-15 | — | — | EP | disclosed |
| US-4189426-A | POLYPEPTIDE | HOFFMANN-LA ROCHE, INC. (US) | 1980-02-19 | — | — | US | disclosed |
| US-3975367-A | PEPTIDE, VIRICIDE, IMMUNOSUPPRESSANT, NEOPLASTIC CELLS | THE UPJOHN COMPANY (US) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203582-A1 | LYSOBACTIN AMIDES | AADAT, HAMP, DLST | CTSS 660/4885CTSK 1058/4885CTSB 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.