Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28507824 | 0.91 | HSD11B1 (0.60) | ALDH1A1MAPTHSD11B1RAB9ANPC1 | |
| SCHEMBL2499199 | 0.91 | NPC1 (0.56) | ALDH1A1MAPTHSD11B1RAB9ANPC1 | |
| SCHEMBL6280282 | 0.89 | MTNR1A (0.51) | ALDH1A1MAPTHSD11B1RAB9ANPC1 | |
| SCHEMBL5043303 | 0.87 | NPC1 (0.52) | ALDH1A1MAPTHSD11B1RAB9ANPC1 | |
| SCHEMBL29766169 | 0.87 | NPC1 (0.52) | ALDH1A1MAPTHSD11B1RAB9ANPC1 | |
| SCHEMBL30610971 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MAPTHSD11B1RAB9ANPC1 | |
| SCHEMBL5045385 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MAPTHSD11B1RAB9ANPC1 | |
| SCHEMBL8597033 | 0.85 | ALDH1A1 (0.52) | ALDH1A1MAPTRAB9ANPC1MTNR1A | |
| SCHEMBL10222071 | 0.84 | CYP1A2 (0.59) | ALDH1A1RAB9ANPC1MTNR1AMTNR1B | |
| SCHEMBL7455151 | 0.84 | MAOB (0.53) | ALDH1A1MAPTRAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075227-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |