Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 7/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599734 | 0.85 | MEN1 (0.42) | NPC1RAB9ADYRK1ACLK1DYRK1B | |
| SCHEMBL11599724 | 0.85 | MAPT (0.45) | CYP2C19RAB9AALDH1A1MEN1LMNA | |
| SCHEMBL11600615 | 0.84 | MEN1 (0.41) | NPC1RAB9ADYRK1ACLK1DYRK1B | |
| SCHEMBL11599564 | 0.82 | MEN1 (0.44) | HSD17B1HSD17B2NPC1RAB9AMEN1 | |
| SCHEMBL11599769 | 0.80 | HTT (0.34) | CYP2C19NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL11599360 | 0.79 | AKR1C3 (0.41) | CA1CA2ALDH1A1MEN1LMNA | |
| SCHEMBL11601667 | 0.78 | ESR1 (0.51) | CYP2C19ALDH1A1MEN1LMNAMAPT | |
| SCHEMBL11600640 | 0.78 | KAT6A (0.44) | NPC1MEN1KMT2A | |
| SCHEMBL11599650 | 0.76 | ALDH1A1 (0.51) | CYP2C19NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL11602342 | 0.75 | KAT6A (0.43) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075227-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |