Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 8/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.46 |
| ▸ | CTRC | Q99895 | 2/20 | 0.45 |
| ▸ | GLB1 | P16278 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11606470 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2NPSR1CTRCGLB1MEN1 | |
| SCHEMBL11605659 | 0.83 | DYRK1A (0.43) | SMN1; SMN2NPSR1PPARAMEN1NPC1 | |
| SCHEMBL11603724 | 0.80 | ALOX5 (0.47) | SMN1; SMN2NPSR1PPARAALOX5MEN1 | |
| SCHEMBL11603794 | 0.80 | PPARA (0.39) | SMN1; SMN2NPSR1PPARAALOX5MEN1 | |
| SCHEMBL11602024 | 0.79 | ALDH1A1 (0.56) | SMN1; SMN2NPSR1MEN1NPC1ALDH1A1 | |
| SCHEMBL8523609 | 0.76 | SMN1; SMN2 (0.74) | SMN1; SMN2NPSR1PPARAALOX5MEN1 | |
| SCHEMBL12585031 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2NPSR1PPARAALOX5MEN1 | |
| SCHEMBL2032147 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2NPSR1PPARAALOX5MEN1 | |
| SCHEMBL11603253 | 0.74 | PPARA (0.50) | SMN1; SMN2PPARANPC1ALDH1A1MAPT | |
| SCHEMBL2033025 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2NPSR1PPARAALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096111-A | (BENZOTHIAZOLYL-THIO)-SUBSTITUTED ANTHRAQUINONES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |