Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601529 | 0.83 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2KMT2ANPSR1MEN1 | |
| SCHEMBL11603794 | 0.80 | PPARA (0.39) | MAPTSMN1; SMN2KMT2ALMNATP53 | |
| SCHEMBL11603724 | 0.80 | ALOX5 (0.47) | DYRK1AMAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL11602024 | 0.79 | ALDH1A1 (0.56) | MAPTSMN1; SMN2KMT2ALMNATP53 | |
| SCHEMBL11606470 | 0.78 | SMN1; SMN2 (0.41) | MAPTSMN1; SMN2KMT2ALMNATP53 | |
| SCHEMBL11604954 | 0.77 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2KMT2ALMNATP53 | |
| SCHEMBL1772108 | 0.76 | PDK1 (0.55) | DYRK1AMAPTSMN1; SMN2LMNATP53 | |
| SCHEMBL11603253 | 0.74 | PPARA (0.50) | DYRK1AMAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL11605260 | 0.74 | KMT2A (0.58) | MAPTSMN1; SMN2KMT2ALMNATP53 | |
| SCHEMBL11601837 | 0.74 | PPARA (0.45) | MAPTSMN1; SMN2KMT2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096111-A | (BENZOTHIAZOLYL-THIO)-SUBSTITUTED ANTHRAQUINONES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |