Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLB1 | P16278 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601529 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2NPSR1MAPTKMT2AMEN1 | |
| SCHEMBL11605659 | 0.78 | DYRK1A (0.43) | SMN1; SMN2NPSR1CTSDMAPTKMT2A | |
| SCHEMBL11603253 | 0.78 | PPARA (0.50) | SMN1; SMN2MAPTKMT2AALDH1A1PKM | |
| SCHEMBL11602024 | 0.77 | ALDH1A1 (0.56) | SMN1; SMN2NPSR1CTSDMAPTKMT2A | |
| SCHEMBL11605260 | 0.75 | KMT2A (0.58) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11606808 | 0.75 | PKM (0.65) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11603794 | 0.75 | PPARA (0.39) | SMN1; SMN2NPSR1CTSDMAPTKMT2A | |
| SCHEMBL11601837 | 0.75 | PPARA (0.45) | SMN1; SMN2NPSR1MAPTKMT2AMEN1 | |
| SCHEMBL11604954 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11603724 | 0.75 | ALOX5 (0.47) | SMN1; SMN2NPSR1CTSDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096111-A | (BENZOTHIAZOLYL-THIO)-SUBSTITUTED ANTHRAQUINONES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |