Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602679 | 0.93 | LIPG (0.38) | TYR | |
| SCHEMBL11604969 | 0.89 | — | — | |
| SCHEMBL11602349 | 0.81 | — | — | |
| SCHEMBL10774428 | 0.76 | ALOX5 (0.44) | TYR | |
| SCHEMBL10371597 | 0.75 | ALOX5 (0.42) | TYR | |
| SCHEMBL10463286 | 0.75 | KDM4E (0.45) | TYRCTRC | |
| SCHEMBL23057956 | 0.74 | LIPG (0.39) | TYR | |
| SCHEMBL5702624 | 0.73 | THRA (0.34) | TYR | |
| SCHEMBL20869442 | 0.72 | TYR (0.39) | TYRCTRCPDE4APDE4BPDE4C | |
| SCHEMBL9243142 | 0.71 | TYR (0.38) | TYRCTRCPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067933-A | OXIDATION RESISTANCE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-01-10 | — | — | US | disclosed |
| US-3959221-A | OXIDATIVE DEGRADATION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-05-25 | — | — | US | disclosed |