SCHEMBL10463286

SCHEMBL10463286

CCCCc1ccsc1OS(C)(=O)=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
GAA P10253 2/20 0.45
LMNA P02545 1/20 0.34
RECQL P46063 1/20 0.34
CA2 P00918 4/20 0.33
CA12 O43570 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
FUT7 Q11130 1/20 0.32
CTRC Q99895 1/20 0.32
ELANE P08246 1/20 0.31
CTSG P08311 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP7 P09237 1/20 0.31
MMP9 P14780 1/20 0.31
MMP14 P50281 1/20 0.31
TYR P14679 1/20 0.31
CA1 P00915 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10462894 0.84 CA12 (0.37) KDM4EALDH1A1GAACA2CA12
SCHEMBL11601586 0.75 TYR (0.33) CTRCTYR
SCHEMBL5702624 0.73 THRA (0.34) ALDH1A1TYR
SCHEMBL10774428 0.73 ALOX5 (0.44) TYR
SCHEMBL10371597 0.71 ALOX5 (0.42) TYR
SCHEMBL1164460 0.71 CA2 (0.47) LMNARECQLCA2CA12SMN1; SMN2
SCHEMBL23057956 0.70 LIPG (0.39) KDM4EALDH1A1LMNATYR
SCHEMBL3655204 0.70 THRA (0.46) KDM4EALDH1A1GAACA2CA12
SCHEMBL27366287 0.70 CTRC (0.37) KDM4EALDH1A1GAALMNARECQL
SCHEMBL10885737 0.70 EDNRB (0.36) KDM4EALDH1A1GAALMNARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4950679-A Alkanesulfonate derivatives and their use as insecticides, acaricides or nematicides NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1990-08-21 US disclosed
US-4791127-A Alkanesulfonate derivatives and their use as insecticides, acaricides or nematicides NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1988-12-13 US disclosed
EP-0245944-A2 Alkanesulfonate derivatives and their use as insecticides, acaricides or nematicides NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1987-11-19 EP disclosed
EP-0220857-A1 Alkanesulfonate derivatives and their use as insecticides, acaricides or nematicides Nippon Kayaku Kabushiki Kaisha (JP) 1987-05-06 EP disclosed
US-4652574-A Certain mono-, di- or tri-substituted pyridyl esters of alkane sulfonic acids having insecticidal, acaricidal and nematocidal properties NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1987-03-24 US disclosed
EP-0182603-A2 Alkanesulfonate derivatives useful as an insecticide, acaricide and nematicide NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1986-05-28 EP disclosed