Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3029796 | 0.86 | HCRTR1 (0.58) | HCRTR1L3MBTL1GLAMAPTMAPK1 | |
| SCHEMBL10592502 | 0.86 | HCRTR1 (0.58) | HCRTR1L3MBTL1GLAMAPTMAPK1 | |
| SCHEMBL11602712 | 0.85 | LMNA (0.59) | L3MBTL1MAPTMAPK1NPSR1MEN1 | |
| Water SCHEMBL11089583 | 0.83 | LMNA (0.57) | L3MBTL1MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL3835541 | 0.82 | LMNA (0.68) | L3MBTL1MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL206583 | 0.81 | HCRTR1 (0.66) | HCRTR1L3MBTL1GLAMAPTMAPK1 | |
| SCHEMBL11763044 | 0.81 | HCRTR1 (0.66) | HCRTR1L3MBTL1GLAMAPTMAPK1 | |
| SCHEMBL6969031 | 0.81 | HCRTR1 (0.66) | HCRTR1L3MBTL1GLAMAPTMAPK1 | |
| SCHEMBL9449107 | 0.80 | HCRTR1 (0.53) | HCRTR1L3MBTL1GLAMAPTMAPK1 | |
| SCHEMBL124831 | 0.79 | ALDH1A1 (0.65) | HCRTR1L3MBTL1GLAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4131686-A | ANTIDIABETIC | TANABE SEIYAKU CO., LTD. (JP) | 1978-12-26 | — | — | US | disclosed |