Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842784 | 0.76 | MAOA (0.42) | MAOAMAOBNFKB1FTOMCL1 | |
| SCHEMBL23219216 | 0.73 | MAOA (0.42) | MAOAMAOBNFKB1FTOHTR2A | |
| SCHEMBL29591435 | 0.73 | MAOA (0.42) | MAOAMAOBNFKB1FTOHTR2A | |
| SCHEMBL30752490 | 0.70 | DAO (0.46) | MAOAMAOBNFKB1CA12CA9 | |
| SCHEMBL29871305 | 0.68 | CA12 (0.57) | CA12CA9MCL1CA1CA3 | |
| SCHEMBL237720 | 0.68 | CA12 (0.57) | CA12CA9MCL1CA1CA3 | |
| SCHEMBL4429415 | 0.67 | PAX8 (0.48) | MAOAMAOBNFKB1FTOHTR2A | |
| Hydrochloric Acid SCHEMBL31179088 | 0.67 | CA12 (0.55) | CA12CA9MCL1CA1CA3 | |
| SCHEMBL30804611 | 0.67 | CA12 (0.55) | CA12CA9MCL1CA1CA3 | |
| SCHEMBL4063814 | 0.67 | MAPT (0.41) | MAOAMAOBNFKB1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372353-A | Difluoroalkylated dihydrofuranoquinolinone derivative and preparation method thereof | 哈尔滨工业大学 | 2021-09-10 | — | — | CN | disclosed |
| US-20120129884-A1 | PHOTOCHEMOTHERAPEUTIC HETEROCYCLIC AGENTS HAVING ANTIPROLIFERATIVE AND ANTINEOPLASTIC ACTIVITY | UNIVERSITA DEGLI STUDI DI PADOVA (IT) | 2012-05-24 | — | — | US | disclosed |
| WO-2011013159-A1 | PHOTOCHEMOTHERAPEUTIC HETEROCYCLIC AGENTS HAVING ANTIPROLIFERATIVE AND ANTINEOPLASTIC ACTIVITY | UNIVERSITÀ DEGLI STUDI DI PADOVA (IT) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129884-A1 | PHOTOCHEMOTHERAPEUTIC HETEROCYCLIC AGENTS HAVING ANTIPROLIFERATIVE AND ANTINEOPLASTIC ACTIVITY | PCNA, ERCC4, UBQLN2 | MAOA 2639/4885MAOB 2686/4885NFKB1 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.