Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11606128 | 0.78 | SMN1; SMN2 (0.34) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11606500 | 0.72 | NPSR1 (0.47) | ALDH1A1MEN1KMT2ARAB9AHSD17B10 | |
| SCHEMBL11602999 | 0.70 | POLB (0.40) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11683084 | 0.68 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11669894 | 0.68 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11682862 | 0.68 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11600436 | 0.66 | MEN1 (0.43) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11670623 | 0.66 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11680854 | 0.66 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11549721 | 0.64 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086238-A | 1-Thiadiazolyl-4-methoxymethyl-5-hydroxyimidazolidinones | VELSICOL CHEMICAL CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |