Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603744 | 0.76 | SMN1; SMN2 (0.41) | ALDH1A1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11603565 | 0.72 | POLQ (0.33) | SMN1; SMN2 | |
| SCHEMBL10567054 | 0.71 | RAB9A (0.51) | POLBGAAALDH1A1RAB9ANPC1 | |
| SCHEMBL11600436 | 0.71 | MEN1 (0.43) | POLBALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL11606128 | 0.71 | SMN1; SMN2 (0.34) | POLBGAAALDH1A1RAB9ANPC1 | |
| SCHEMBL11688824 | 0.70 | RAB9A (0.42) | POLBALDH1A1RAB9ANPC1CYP1A2 | |
| SCHEMBL11604480 | 0.70 | GLS (0.38) | ALDH1A1RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL11372313 | 0.69 | RAB9A (0.55) | POLBALDH1A1RAB9ANPC1NTSR1 | |
| SCHEMBL11606500 | 0.69 | NPSR1 (0.47) | POLBALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL11604523 | 0.69 | SMN1; SMN2 (0.36) | POLBGAAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086238-A | 1-Thiadiazolyl-4-methoxymethyl-5-hydroxyimidazolidinones | VELSICOL CHEMICAL CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |