Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GLS | O94925 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11607162 | 0.81 | CA1 (0.38) | SMN1; SMN2RAB9ANPC1MEN1MAPT | |
| SCHEMBL11601840 | 0.78 | ALDH1A1 (0.43) | SMN1; SMN2RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL11601845 | 0.75 | CA1 (0.38) | MEN1KMT2A | |
| SCHEMBL11602999 | 0.71 | POLB (0.40) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL11606500 | 0.70 | NPSR1 (0.47) | SMN1; SMN2RAB9AALDH1A1HSD17B10GLS | |
| SCHEMBL11603744 | 0.70 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9AALDH1A1HSD17B10HPGD | |
| SCHEMBL11688050 | 0.67 | — | — | |
| SCHEMBL11600436 | 0.67 | MEN1 (0.43) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL11551181 | 0.66 | — | — | |
| SCHEMBL11588010 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086238-A | 1-Thiadiazolyl-4-methoxymethyl-5-hydroxyimidazolidinones | VELSICOL CHEMICAL CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |