Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 11/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603744 | 0.77 | SMN1; SMN2 (0.41) | GLSSMN1; SMN2HSD17B10RAB9AALDH1A1 | |
| SCHEMBL11604523 | 0.75 | SMN1; SMN2 (0.36) | GLSSMN1; SMN2HSD17B10ALDH1A1MAPT | |
| SCHEMBL11600436 | 0.73 | MEN1 (0.43) | SMN1; SMN2RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL11606128 | 0.73 | SMN1; SMN2 (0.34) | GLSSMN1; SMN2HSD17B10RAB9AALDH1A1 | |
| SCHEMBL11603565 | 0.73 | POLQ (0.33) | SMN1; SMN2 | |
| SCHEMBL11606500 | 0.71 | NPSR1 (0.47) | GLSSMN1; SMN2HSD17B10RAB9AALDH1A1 | |
| SCHEMBL11602999 | 0.70 | POLB (0.40) | SMN1; SMN2RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL11552092 | 0.69 | GLS (0.39) | GLSSMN1; SMN2HSD17B10RAB9AALDH1A1 | |
| SCHEMBL11858443 | 0.68 | GLS (0.39) | GLSSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL10584030 | 0.67 | GLS (0.48) | GLSSMN1; SMN2RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086238-A | 1-Thiadiazolyl-4-methoxymethyl-5-hydroxyimidazolidinones | VELSICOL CHEMICAL CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |