Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 19/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11604523 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL11603558 | 0.81 | SMN1; SMN2 (0.35) | POLQSMN1; SMN2 | |
| SCHEMBL11603744 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2 | |
| SCHEMBL11601845 | 0.74 | CA1 (0.38) | — | |
| SCHEMBL11607162 | 0.73 | CA1 (0.38) | SMN1; SMN2 | |
| SCHEMBL11604480 | 0.73 | GLS (0.38) | SMN1; SMN2 | |
| SCHEMBL11602999 | 0.72 | POLB (0.40) | SMN1; SMN2 | |
| SCHEMBL11606128 | 0.72 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL11600436 | 0.70 | MEN1 (0.43) | SMN1; SMN2 | |
| SCHEMBL11689196 | 0.70 | POLQ (0.37) | POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086238-A | 1-Thiadiazolyl-4-methoxymethyl-5-hydroxyimidazolidinones | VELSICOL CHEMICAL CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |