Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.38 |
| ▸ | CA2 | P00918 | 10/20 | 0.38 |
| ▸ | CA4 | P22748 | 9/20 | 0.38 |
| ▸ | CA9 | Q16790 | 9/20 | 0.38 |
| ▸ | CA12 | O43570 | 7/20 | 0.38 |
| ▸ | CA3 | P07451 | 7/20 | 0.38 |
| ▸ | CA6 | P23280 | 7/20 | 0.38 |
| ▸ | CA5A | P35218 | 7/20 | 0.38 |
| ▸ | CA7 | P43166 | 7/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 7/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601845 | 0.94 | CA1 (0.38) | CA1CA2CA4CA9CA12 | |
| SCHEMBL11606128 | 0.81 | SMN1; SMN2 (0.34) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11601840 | 0.78 | ALDH1A1 (0.43) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL10565445 | 0.76 | MAPT (0.47) | CA1CA2CA4CA9CA12 | |
| SCHEMBL11704507 | 0.75 | CA1 (0.47) | CA1CA2CA4CA9CA12 | |
| SCHEMBL11604480 | 0.74 | GLS (0.38) | MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL11603565 | 0.73 | POLQ (0.33) | SMN1; SMN2 | |
| SCHEMBL11602999 | 0.72 | POLB (0.40) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11606500 | 0.71 | NPSR1 (0.47) | MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL11690673 | 0.71 | CA1 (0.43) | CA1CA2CA4CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086238-A | 1-Thiadiazolyl-4-methoxymethyl-5-hydroxyimidazolidinones | VELSICOL CHEMICAL CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |