Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13194702 | 0.81 | NPC1 (0.35) | ALDH1A1MAPTALOX15SMN1; SMN2KDM4E | |
| SCHEMBL15490061 | 0.77 | OPRM1 (0.38) | GAAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4751291 | 0.77 | HHAT (0.38) | MAPTALOX15SMN1; SMN2TSHR | |
| SCHEMBL19722754 | 0.76 | NPC1 (0.38) | ALOX15TSHR | |
| SCHEMBL14970374 | 0.76 | HHAT (0.43) | LMNA | |
| SCHEMBL30309375 | 0.69 | PDE4B (0.40) | MAPTKDM4E | |
| SCHEMBL4751946 | 0.69 | HHAT (0.45) | KMT2A | |
| SCHEMBL3307502 | 0.69 | HHAT (0.45) | KMT2A | |
| SCHEMBL3307496 | 0.69 | HHAT (0.45) | KMT2A | |
| SCHEMBL11604417 | 0.68 | LHCGR (0.48) | ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076819-A | ANTIINFLAMMATORY AGENTS, INHIBITOR OF BLOOD PLATELET AGGREGATION | PARCOR (FR) | 1978-02-28 | — | — | US | disclosed |