Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18650801 | 0.78 | PER2 (0.34) | HSD11B1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL29348251 | 0.76 | PER2 (0.35) | HSD11B1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL16503637 | 0.74 | HSD11B1 (0.30) | HSD11B1 | |
| SCHEMBL11605327 | 0.72 | GRIN1 (0.41) | — | |
| SCHEMBL20609926 | 0.72 | OPRM1 (0.30) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL18806202 | 0.71 | HRH3 (0.36) | HSD11B1 | |
| SCHEMBL13431755 | 0.69 | PRMT1 (0.37) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL20420099 | 0.69 | ACACB (0.33) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL13216615 | 0.68 | RARA (0.35) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL21061534 | 0.68 | PRMT1 (0.37) | OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067985-A | IMMUNOSUPPRESSIVE, SEDATIVE, ANTITUMOR | CHEMIE GRUNENTHAL GMBH (DT) | 1978-01-10 | — | — | US | disclosed |
| US-3951985-A | SUBSTITUTED ORTHO-SULFOBENZOIC ACID IMIDO PYRROLIDONE, PIPERIDONE OR CAPROLACTAM | CHEMIE GRUNENTHAL GMBH (DT) | 1976-04-20 | — | — | US | disclosed |