Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.65 |
| ▸ | XDH | P47989 | 6/20 | 0.65 |
| ▸ | FTO | Q9C0B1 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | BCHE | P06276 | 4/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.65 |
| ▸ | ACHE | P22303 | 4/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.65 |
| ▸ | CA12 | O43570 | 4/20 | 0.65 |
| ▸ | PPARG | P37231 | 4/20 | 0.65 |
| ▸ | CA7 | P43166 | 4/20 | 0.65 |
| ▸ | TRPC5 | Q9UL62 | 4/20 | 0.65 |
| ▸ | MAOA | P21397 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17620177 | 0.87 | ABCB1 (0.68) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| SCHEMBL22710103 | 0.84 | POLH (0.52) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| SCHEMBL17620272 | 0.84 | POLH (0.66) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| SCHEMBL14254528 | 0.84 | MEN1 (0.65) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| SCHEMBL17620220 | 0.83 | POLH (0.60) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| SCHEMBL17620269 | 0.82 | POLH (0.52) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| Galangin SCHEMBL29393121 | 0.80 | MEN1 (1.00) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| Galangin SCHEMBL117225 | 0.80 | MEN1 (1.00) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| Quercetin SCHEMBL4173190 | 0.78 | MEN1 (0.87) | MEN1KMT2ACYP1A2ABCB1CYP1A1 | |
| Quercetin SCHEMBL3958393 | 0.78 | MEN1 (0.87) | MEN1KMT2ACYP1A2ABCB1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104416-A1 | COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE | MEDICAL AND PHARMACEUTICAL INDUSTRY TECHNOLOGY AND DEVELOPMENT CENTER (CN) | 2021-06-03 | — | — | WO | disclosed |
| US-20210139447-A1 | Lipophenolic Flavonoid Derivatives Useful To Reduce Carbonyl And Oxidative Stresses (COS) | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2021-05-13 | — | — | US | disclosed |
| EP-2627691-B1 | DEGRADABLE POLYCARBONATES | TEXAS A&M UNIV (US) | 2020-11-25 | — | — | EP | disclosed |
| WO-2020012003-A1 | LIPOPHENOLIC FLAVONOID DERIVATIVES USEFUL TO REDUCE CARBONYL AND OXIDATIVE STRESSES (COS) | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2020-01-16 | — | — | WO | disclosed |
| EP-2460810-B1 | NOVEL FLAVANONE DERIVATIVE | UNIV OKAYAMA NAT UNIV CORP (JP) | 2015-07-15 | — | — | EP | disclosed |
| US-8916526-B2 | Flavanone derivative | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2014-12-23 | — | — | US | disclosed |
| US-20120202980-A1 | Novel Flavanone Derivative | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2012-08-09 | — | — | US | disclosed |
| EP-2468741-A1 | Novel quercetin derivatives, their preparation, pharmaceutical compositions containing them and their use | Bel/Novamann International s.r.o. (SK) | 2012-06-27 | — | — | EP | disclosed |
| EP-2460810-A1 | NOVEL FLAVANONE DERIVATIVE | National University Corporation Okayama University (JP) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011013735-A1 | NOVEL FLAVANONE DERIVATIVE | 国立大学法人 岡山大学 (JP) | 2011-02-03 | — | — | WO | disclosed |
| US-20090182133-A1 | BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-VIRAL AGENTS | SINGAPORE POLYTECHNIC | 2009-07-16 | — | — | US | disclosed |
| US-20090182133-A1 | BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-VIRAL AGENTS | SINGAPORE POLYTECHNIC | 2009-07-16 | — | — | US | disclosed |
| US-20090182133-A1 | BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-VIRAL AGENTS | SINGAPORE POLYTECHNIC | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182133-A1 | BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-VIRAL AGENTS | SARS1, MAVS, ACE2 | MEN1 4730/4885KMT2A 3631/4885CYP1A2 819/4885 |
| US-20120202980-A1 | Novel Flavanone Derivative | GALE, VRK1, GALK1 | MEN1 4827/4885KMT2A 2320/4885CYP1A2 596/4885 |
| US-20210139447-A1 | Lipophenolic Flavonoid Derivatives Useful To Reduce Carbonyl And Oxidative Stresses (COS) | LPO, NQO1, CAT | MEN1 3920/4885KMT2A 4226/4885CYP1A2 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.