Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.68 |
| ▸ | POLH | Q9Y253 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | APEX1 | P27695 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MMP1 | P03956 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.63 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.61 |
| ▸ | TUBB | P07437 | 1/20 | 0.61 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17620272 | 0.90 | POLH (0.66) | ABCB1POLHKDM4EPOLBAPEX1 | |
| SCHEMBL17620220 | 0.88 | POLH (0.60) | ABCB1POLHKDM4EPOLBAPEX1 | |
| SCHEMBL22710103 | 0.88 | POLH (0.52) | ABCB1POLHKDM4EPOLBAPEX1 | |
| SCHEMBL17620269 | 0.87 | POLH (0.52) | ABCB1POLHKDM4EPOLBAPEX1 | |
| SCHEMBL1160941 | 0.87 | MEN1 (0.65) | ABCB1POLHKDM4EPOLBAPEX1 | |
| SCHEMBL21621458 | 0.82 | ADORA3 (0.57) | ABCB1POLHKDM4EPOLBAPEX1 | |
| SCHEMBL4631662 | 0.82 | ABCB1 (1.00) | ABCB1POLHKDM4EPOLBAPEX1 | |
| 3-O-Methylquercetin SCHEMBL380558 | 0.79 | POLH (1.00) | ABCB1POLHKDM4EPOLBAPEX1 | |
| 3-O-Methylquercetin SCHEMBL29897544 | 0.79 | POLH (1.00) | ABCB1POLHKDM4EPOLBAPEX1 | |
| Isokaempferide SCHEMBL1628023 | 0.78 | POLH (1.00) | ABCB1POLHKDM4EPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016041195-A1 | FLAVONE GLYCOSIDE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | 贵州百灵企业集团制药股份有限公司 | 2016-03-24 | — | — | WO | disclosed |