Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11616001 | 0.82 | ALDH1A1 (0.64) | ALDH1A1POLBMAPK1KDM4ETP53 | |
| SCHEMBL478909 | 0.82 | ALDH1A1 (0.64) | ALDH1A1POLBMAPK1KDM4ETP53 | |
| SCHEMBL4609039 | 0.82 | ALDH1A1 (0.64) | ALDH1A1POLBMAPK1KDM4ETP53 | |
| SCHEMBL11610029 | 0.77 | LMNA (0.46) | ALDH1A1POLBMAPK1KDM4ETP53 | |
| SCHEMBL30165546 | 0.73 | POLB (0.71) | ALDH1A1POLBMAPK1KDM4ETP53 | |
| SCHEMBL2888134 | 0.73 | POLB (0.71) | ALDH1A1POLBMAPK1KDM4ETP53 | |
| SCHEMBL8431996 | 0.73 | POLB (0.62) | ALDH1A1POLBMAPK1KDM4ETP53 | |
| SCHEMBL8431990 | 0.73 | POLB (0.62) | ALDH1A1POLBMAPK1KDM4ETP53 | |
| SCHEMBL512864 | 0.73 | ALDH1A1 (0.68) | ALDH1A1POLBMAPK1KDM4ETP53 | |
| SCHEMBL10201311 | 0.73 | ALDH1A1 (0.68) | ALDH1A1POLBMAPK1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3951980-A | 3-Substituted-8-methyl-3,8-diazabicyclo[3.2.1]octanes | STANFORD RESEARCH INSTITUTE (US) | 1976-04-20 | — | — | US | disclosed |
| US-3947445-A | Diazabicyclooctanes and diazabicycloheptanes | STANFORD RESEARCH INSTITUTE (US) | 1976-03-30 | — | — | US | disclosed |