Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11744950 | 0.87 | ALDH1A1 (0.51) | LMNAALDH1A1MAPTCYP3A4KDM4E | |
| SCHEMBL11744939 | 0.87 | ALDH1A1 (0.51) | LMNAALDH1A1MAPTCYP3A4KDM4E | |
| SCHEMBL11616238 | 0.84 | MAPT (0.42) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL343409 | 0.82 | HTT (0.47) | LMNAALDH1A1MAPTCYP3A4KDM4E | |
| SCHEMBL343408 | 0.82 | ALDH1A1 (0.43) | LMNAALDH1A1MAPTCYP3A4KDM4E | |
| SCHEMBL1941394 | 0.81 | HTT (0.46) | LMNAALDH1A1MAPTCYP3A4KDM4E | |
| SCHEMBL10966789 | 0.80 | PPIA (0.40) | ALDH1A1VCAM1CYP1A2GAAL3MBTL1 | |
| Methyl Alcohol SCHEMBL28097248 | 0.79 | LMNA (0.55) | LMNAALDH1A1MAPTCYP3A4KDM4E | |
| SCHEMBL9354657 | 0.79 | PKM (0.49) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL2849735 | 0.79 | TSHR (0.54) | ALDH1A1MAPTKDM4EKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4066457-A | P-PHENYLENEDIAMINE DERIVATIVES | GAF CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |