Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310130 | 0.96 | LMNA (0.54) | LMNAMAPTALDH1A1CYP3A4KDM4E | |
| SCHEMBL31188768 | 0.96 | LMNA (0.54) | LMNAMAPTALDH1A1CYP3A4KDM4E | |
| SCHEMBL11661312 | 0.89 | ALDH1A1 (0.48) | LMNAMAPTALDH1A1CYP3A4KDM4E | |
| SCHEMBL10983166 | 0.87 | LMNA (0.51) | LMNAMAPTALDH1A1CYP3A4KDM4E | |
| SCHEMBL30435204 | 0.85 | MERTK (0.51) | LMNAMAPTALDH1A1CYP3A4KDM4E | |
| SCHEMBL8536622 | 0.85 | MERTK (0.51) | LMNAMAPTALDH1A1CYP3A4KDM4E | |
| SCHEMBL10814747 | 0.85 | ALDH1A1 (0.51) | LMNAMAPTALDH1A1CYP3A4KDM4E | |
| SCHEMBL2874199 | 0.85 | LMNA (0.50) | LMNAMAPTALDH1A1CYP3A4KDM4E | |
| SCHEMBL10778338 | 0.84 | ALDH1A1 (0.62) | LMNAMAPTALDH1A1CYP3A4KDM4E | |
| SCHEMBL19899586 | 0.84 | LMNA (0.50) | LMNAMAPTALDH1A1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105949069-A | Method for continuous hydrogenation production of 4-chloro-2,5-dimethoxyaniline | 济南和润化工科技有限公司 | 2016-09-21 | — | — | CN | claimed |