Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10528811 | 0.79 | GLS (0.42) | RAB9ANPC1CYP1A2MAPTKMT2A | |
| SCHEMBL11611109 | 0.77 | NR4A1 (0.43) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11610680 | 0.72 | CYP2C19 (0.38) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9004751 | 0.71 | LMNA (0.40) | RAB9ANPC1KDM4EMAPTKMT2A | |
| SCHEMBL11611329 | 0.67 | LMNA (0.36) | RAB9ANPC1CYP1A2CYP3A4KDM4E | |
| SCHEMBL11608320 | 0.66 | EPHX1 (0.42) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3781903 | 0.66 | KDM4E (0.54) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11608131 | 0.66 | NR4A1 (0.41) | RAB9AKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL9718676 | 0.65 | LMNA (0.46) | RAB9ANPC1CYP3A4CYP2C19KDM4E | |
| 1-Naphthol SCHEMBL28993869 | 0.65 | CYP1A2 (0.53) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072694-A | Dioxolane derivatives and use as photoinitiators | LEE PHARMACEUTICALS (US) | 1978-02-07 | — | — | US | disclosed |