Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11611329 | 0.86 | LMNA (0.36) | GLSLMNACYP1A2CES2CES1 | |
| SCHEMBL14453309 | 0.83 | LMNA (0.35) | LMNACES2CES1TSHROPRM1 | |
| SCHEMBL11491382 | 0.82 | LMNA (0.38) | GLSLMNACYP1A2CES2CES1 | |
| SCHEMBL8765171 | 0.81 | LMNA (0.41) | LMNACES2CES1TSHROPRM1 | |
| SCHEMBL9718669 | 0.81 | AKR1C1 (0.39) | LMNACYP1A2SLC6A2SLC6A3TSHR | |
| SCHEMBL11611109 | 0.79 | NR4A1 (0.43) | GLSLMNACYP1A2TSHRKMT2A | |
| SCHEMBL11612974 | 0.79 | RAB9A (0.38) | LMNACYP1A2SLC6A2SLC6A3TSHR | |
| SCHEMBL9004751 | 0.79 | LMNA (0.40) | LMNACES2CES1CHRNB2SLC6A2 | |
| SCHEMBL6326779 | 0.74 | LMNA (0.36) | LMNACES2CES1TSHROPRM1 | |
| SCHEMBL10414654 | 0.74 | CES2 (0.47) | LMNACES2CES1CHRNB2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221010-B1 | PHOTO-INITIATOR SYSTEMS FOR FREE-RADICAL POLYMERISATIONS | CIBA-GEIGY AG (CH) | 1989-04-26 | — | — | EP | disclosed |
| EP-0221010-A1 | Photo-initiator systems for free-radical polymerisations | CIBA-GEIGY AG (CH) | 1987-05-06 | — | — | EP | disclosed |
| US-4229274-A | PHOTOINITIATOR, PHOTOSENSITIZER, QUENCHER, AND COMPOUNDS CONTAINING ACRYLYLOXY GROUPS | PPG INDUSTRIES, INC. (US) | 1980-10-21 | — | — | US | disclosed |
| US-4072694-A | Dioxolane derivatives and use as photoinitiators | LEE PHARMACEUTICALS (US) | 1978-02-07 | — | — | US | disclosed |