Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13865134 | 0.88 | KMT2A (0.51) | KMT2AHPGDSMN1; SMN2RAB9ATSHR | |
| SCHEMBL29175057 | 0.86 | TAAR1 (0.48) | SMN1; SMN2RAB9AGAAMAPTALDH1A1 | |
| SCHEMBL11613615 | 0.85 | KMT2A (0.61) | KMT2AHPGDSMN1; SMN2RAB9ATSHR | |
| SCHEMBL9125404 | 0.78 | HPGD (0.59) | KMT2AHPGDSMN1; SMN2RAB9ATSHR | |
| SCHEMBL14112017 | 0.76 | KMT2A (0.65) | KMT2AHPGDSMN1; SMN2RAB9ATSHR | |
| SCHEMBL13865117 | 0.75 | MAPT (0.52) | KMT2AHPGDSMN1; SMN2RAB9AGAA | |
| SCHEMBL7527675 | 0.74 | MAPT (0.64) | KMT2AHPGDSMN1; SMN2RAB9AGAA | |
| SCHEMBL9124359 | 0.74 | KMT2A (0.63) | KMT2AHPGDSMN1; SMN2RAB9ATSHR | |
| SCHEMBL2332155 | 0.74 | TSHR (0.56) | KMT2ASMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL28428860 | 0.74 | TSHR (0.56) | KMT2ASMN1; SMN2TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009057133-A2 | A PROCESS FOR THE SYNTHESIS OF 2-[2-[4-[(4-CHLOROPHENYL)PHENYL METHYL]-1-PIPERAZINYL] ETHOXY ACETIC ACID | GLENMARK GENERICS LIMITED (IN) | 2009-05-07 | — | — | WO | disclosed |