Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11614960 | 0.72 | MAPT (0.42) | MAPTMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL11615766 | 0.70 | KMT2A (0.41) | MEN1KMT2ALMNACYP1A2CYP2C19 | |
| SCHEMBL11613055 | 0.69 | MAPT (0.43) | MAPTMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL11506997 | 0.69 | CYP1A2 (0.42) | MAPTMEN1KMT2ALMNARBBP9 | |
| SCHEMBL11616262 | 0.68 | PTGDR2 (0.47) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL11611124 | 0.66 | NPC1 (0.47) | MEN1KMT2ALMNACYP2C19ALDH1A1 | |
| SCHEMBL11613221 | 0.64 | MAPT (0.44) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL27639822 | 0.64 | MAPT (0.53) | PLA2G4AMAPTMEN1KMT2ALMNA | |
| SCHEMBL11613046 | 0.63 | NPC1 (0.43) | MEN1KMT2ALMNACYP2C19ALDH1A1 | |
| SCHEMBL11612175 | 0.63 | KMT2A (0.45) | MAPTMEN1KMT2ACYP1A2KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |