Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11614849 | 0.79 | NPSR1 (0.49) | MAPTALDH1A1LMNANPC1TP53 | |
| SCHEMBL11618199 | 0.79 | KMT2A (0.37) | MAPTALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL11617777 | 0.76 | PTGER4 (0.41) | MAPTKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL11612175 | 0.75 | KMT2A (0.45) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL11612313 | 0.74 | HPGD (0.48) | MAPTALDH1A1LMNARAB9AL3MBTL1 | |
| SCHEMBL11616738 | 0.73 | MAPK1 (0.45) | MAPTKDM4EALDH1A1LMNARAB9A | |
| SCHEMBL11615397 | 0.73 | LMNA (0.45) | MAPTKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL11616262 | 0.72 | PTGDR2 (0.47) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL29114305 | 0.70 | KMT2A (0.58) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11615339 | 0.66 | KMT2A (0.49) | MAPTKDM4EALDH1A1NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |