Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11611124 | 0.82 | NPC1 (0.47) | PTGDR2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL11615839 | 0.81 | PTGDR2 (0.47) | PTGDR2ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL11614755 | 0.81 | DRD3 (0.39) | PTGDR2KDM4EALDH1A1POLBKMT2A | |
| SCHEMBL11616738 | 0.73 | MAPK1 (0.45) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL11613221 | 0.72 | MAPT (0.44) | PTGDR2KDM4EALDH1A1POLBKMT2A | |
| SCHEMBL11618315 | 0.70 | PTGDR2 (0.48) | PTGDR2KDM4EALDH1A1POLBLMNA | |
| SCHEMBL11614313 | 0.70 | NPC1 (0.44) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL11613055 | 0.70 | MAPT (0.43) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL11611744 | 0.69 | GRN (0.43) | KDM4EALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL11613140 | 0.69 | SMN1; SMN2 (0.44) | KDM4EALDH1A1POLBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |