Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686836 | 0.83 | HPGD (0.39) | SMN1; SMN2HPGDHSD17B10MAPTMGLL | |
| SCHEMBL608887 | 0.80 | HSD17B10 (0.48) | SMN1; SMN2HPGDHSD17B10MAPTMGLL | |
| SCHEMBL28296510 | 0.76 | HSD17B10 (0.44) | SMN1; SMN2HPGDHSD17B10MAPTMGLL | |
| SCHEMBL3075964 | 0.76 | HSD17B10 (0.39) | SMN1; SMN2HPGDHSD17B10MAPTMGLL | |
| SCHEMBL10354348 | 0.74 | HPGD (0.42) | SMN1; SMN2HPGDHSD17B10MAPTMGLL | |
| SCHEMBL11615005 | 0.72 | HSD17B10 (0.50) | SMN1; SMN2HPGDHSD17B10MAPTMGLL | |
| SCHEMBL11443761 | 0.71 | ALDH1A1 (0.39) | SMN1; SMN2HPGDHSD17B10TSHRALDH1A1 | |
| SCHEMBL13708152 | 0.70 | MTNR1A (0.49) | SMN1; SMN2HPGDALDH1A1LMNARAB9A | |
| SCHEMBL3066922 | 0.70 | MAPT (0.34) | SMN1; SMN2HPGDHSD17B10MAPTMGLL | |
| SCHEMBL3915092 | 0.69 | ALDH1A1 (0.37) | SMN1; SMN2HPGDTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169969-A2 | Sulphamoylguanidine derivatives | HOECHST UK LIMITED (GB) | 1986-02-05 | — | — | EP | disclosed |