Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 4/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.43 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.43 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10038040 | 0.81 | PPOX (0.43) | PPOXMT-CO2KMT2AMEN1CYP2C19 | |
| SCHEMBL11615277 | 0.80 | ALDH1A1 (0.51) | PTGS1PTGS2MT-CO1MT-CO2HTT | |
| SCHEMBL11611893 | 0.78 | KMT2A (0.42) | PPOXKMT2ALMNAMEN1 | |
| SCHEMBL6784295 | 0.74 | SMN1; SMN2 (0.46) | PTGS1PTGS2MT-CO1MT-CO2HTT | |
| SCHEMBL6788699 | 0.70 | CCNA2 (0.55) | PTGS1PTGS2MT-CO1MT-CO2HTT | |
| SCHEMBL6790452 | 0.69 | CCNA2 (0.56) | PTGS1PTGS2MT-CO1MT-CO2HTT | |
| Mexoprofen SCHEMBL2111806 | 0.68 | PTGS1 (0.47) | PTGS1PTGS2MT-CO1MT-CO2HTT | |
| Mexoprofen SCHEMBL11858696 | 0.68 | PTGS1 (0.47) | PTGS1PTGS2MT-CO1MT-CO2HTT | |
| SCHEMBL6783378 | 0.68 | LMNA (0.50) | PTGS1PTGS2MT-CO1MT-CO2HTT | |
| SCHEMBL6789700 | 0.68 | PHGDH (0.42) | PTGS1PTGS2MT-CO1MT-CO2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4116972-A | ANTI-INFLAMMATORY 1-OXO-ISOINDOLINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | FUJI CHEMICAL INDUSTRY COMPANY LIMITED (JP) | 1978-09-26 | — | — | US | disclosed |