Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.48 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.48 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784295 | 0.80 | SMN1; SMN2 (0.46) | GAAKMT2APTGS1PTGS2MT-CO1 | |
| SCHEMBL11615140 | 0.80 | PPOX (0.43) | GAAKMT2APTGS1PTGS2MT-CO1 | |
| SCHEMBL6790912 | 0.76 | CA12 (0.56) | GAAKMT2AL3MBTL1POLBPTGS1 | |
| SCHEMBL6788274 | 0.74 | MGLL (0.65) | GAAKMT2APTGS1PTGS2MEN1 | |
| SCHEMBL13265283 | 0.74 | LMNA (0.59) | ALDH1A1GAAHPGDKMT2APOLB | |
| SCHEMBL5645885 | 0.74 | ALDH1A1 (0.58) | ALDH1A1GAAHPGDKMT2AL3MBTL1 | |
| SCHEMBL6790452 | 0.73 | CCNA2 (0.56) | GAAKMT2APTGS1PTGS2MT-CO1 | |
| SCHEMBL10038048 | 0.73 | ALDH1A1 (0.64) | ALDH1A1GAAHPGDKMT2AL3MBTL1 | |
| SCHEMBL11421692 | 0.73 | ALDH1A1 (0.64) | ALDH1A1GAAHPGDKMT2AL3MBTL1 | |
| SCHEMBL8114805 | 0.73 | KMT2A (0.45) | ALDH1A1GAAHPGDKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4116972-A | ANTI-INFLAMMATORY 1-OXO-ISOINDOLINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | FUJI CHEMICAL INDUSTRY COMPANY LIMITED (JP) | 1978-09-26 | — | — | US | disclosed |