Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2810870 | 0.90 | HDAC1 (0.58) | HSD11B1L3MBTL1CA12CA1CA2 | |
| SCHEMBL27466099 | 0.89 | MMP2 (0.59) | HSD11B1L3MBTL1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL5124026 | 0.89 | HDAC1 (0.57) | HSD11B1L3MBTL1CA12CA1CA2 | |
| SCHEMBL7771540 | 0.89 | HDAC1 (0.66) | HSD11B1L3MBTL1CA12CA1CA2 | |
| SCHEMBL11466743 | 0.87 | HDAC1 (0.69) | HSD11B1L3MBTL1CA12CA1CA2 | |
| SCHEMBL2807341 | 0.87 | HDAC1 (0.69) | HSD11B1L3MBTL1CA12CA1CA2 | |
| SCHEMBL7773680 | 0.87 | HDAC1 (0.69) | HSD11B1L3MBTL1CA12CA1CA2 | |
| SCHEMBL8189068 | 0.85 | MMP1 (0.69) | HSD11B1POLBSMN1; SMN2HTTKMT2A | |
| SCHEMBL1001018 | 0.83 | HSD11B1 (0.69) | HSD11B1L3MBTL1CA12CA1CA2 | |
| SCHEMBL5466697 | 0.82 | HSD11B1 (0.58) | HSD11B1L3MBTL1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2461683-A1 | BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS | Biogen Idec MA Inc. (US) | 2012-06-13 | — | — | EP | claimed |
| WO-2011017561-A1 | BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS | BIOGEN IDEC MA INC. (US) | 2011-02-10 | — | — | WO | claimed |
| EP-1660507-B9 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON INC (US) | 2010-03-24 | — | — | EP | claimed |
| EP-1660507-B1 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON INC (US) | 2009-08-05 | — | — | EP | claimed |
| EP-1670804-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC Biotech AG (DE) | 2006-06-21 | — | — | EP | claimed |
| WO-2005023818-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC BIOTECH AG (DE) | 2005-03-17 | — | — | WO | claimed |
| EP-0975421-A2 | PREPARATION OF LOW-DUST STABILISERS | Ciba SC Holding AG (CH) | 2000-02-02 | — | — | EP | claimed |
| WO-1998046342-A2 | PREPARATION OF LOW-DUST STABILISERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1998-10-22 | — | — | WO | claimed |
| EP-0415631-B1 | Electrodeposition of palladium films | AMERICAN TELEPHONE & TELEGRAPH (US) | 1994-05-18 | — | — | EP | claimed |
| EP-0415631-A1 | Electrodeposition of palladium films | AT&T Corp. (US) | 1991-03-06 | — | — | EP | claimed |
| US-4911799-A | Electrodeposition of palladium films | AT&T BELL LABORATORIES (US) | 1990-03-27 | — | — | US | claimed |
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |
| WO-2023202625-A1 | FGFR2 INHIBITOR AND METHOD FOR USING SAME | 深圳福沃药业有限公司 | 2023-10-26 | — | — | WO | disclosed |
| CN-116903628-A | FGFR2 inhibitors and methods of use | 深圳福沃药业有限公司 | 2023-10-20 | — | — | CN | disclosed |
| US-10233152-B2 | LSD1 inhibitors | Mirati Therapeutics, Inc. (US) | 2019-03-19 | — | — | US | disclosed |
| US-4911799-A | Electrodeposition of palladium films | AT&T BELL LABORATORIES (US) | 1990-03-27 | — | — | US | disclosed |
| US-4911799-A | Electrodeposition of palladium films | AT&T BELL LABORATORIES (US) | 1990-03-27 | — | — | US | disclosed |
| US-4515596-A | Process for aftertreating dyed fibrous material made of or containing cellulose | CIBA-GEIGY CORPORATION (US) | 1985-05-07 | — | — | US | disclosed |
| US-4017256-A | FIBER DYEABLE WITH DISPERSE DYES AND FIBER DYEABLE WITH REACTIVE DYES | CIBA-GEIGY CORPORATION (US) | 1977-04-12 | — | — | US | disclosed |
| US-3951588-A | Process for dyeing and printing or optical brightening of cellulose materials | CIBA-GEIGY CORPORATION (US) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10233152-B2 | LSD1 inhibitors | KDM1B, KDM1A, KDM3A | HSD11B1 1315/4885L3MBTL1 1119/4885CA12 4254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.