SCHEMBL1001018

SCHEMBL1001018

O=C(O)CCS(=O)(=O)c1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.69
HTT P42858 2/20 0.62
NPSR1 Q6W5P4 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
KDM4E B2RXH2 1/20 0.61
APEX1 P27695 1/20 0.58
ALDH1A1 P00352 1/20 0.58
MAPT P10636 1/20 0.54
HDAC3 O15379 1/20 0.54
HDAC4 P56524 1/20 0.54
HDAC1 Q13547 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC10 Q969S8 1/20 0.54
HDAC11 Q96DB2 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
HDAC9 Q9UKV0 1/20 0.54
HDAC5 Q9UQL6 1/20 0.54
POLB P06746 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10584023 0.98 HSD11B1 (0.67) HSD11B1HTTNPSR1L3MBTL1KDM4E
SCHEMBL7010023 0.88 MMP2 (0.68) HSD11B1HTTNPSR1L3MBTL1KDM4E
SCHEMBL5128861 0.88 HDAC1 (0.60) HSD11B1HTTNPSR1L3MBTL1KDM4E
Hydrochloric Acid SCHEMBL5120938 0.86 HDAC1 (0.58) HSD11B1HTTNPSR1L3MBTL1KDM4E
SCHEMBL6683339 0.86 HDAC1 (0.68) HSD11B1HTTNPSR1L3MBTL1ALDH1A1
SCHEMBL7075505 0.85 HSD11B1 (0.62) HSD11B1HTTNPSR1L3MBTL1KDM4E
SCHEMBL1007843 0.84 HDAC1 (0.71) HSD11B1L3MBTL1ALDH1A1MAPTHDAC3
SCHEMBL10584726 0.84 HDAC1 (0.71) HSD11B1L3MBTL1ALDH1A1MAPTHDAC3
SCHEMBL9754532 0.84 HDAC1 (0.71) HSD11B1L3MBTL1ALDH1A1MAPTHDAC3
SCHEMBL10584107 0.84 HDAC1 (0.71) HSD11B1L3MBTL1ALDH1A1MAPTHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-119978328-A Polybutylene terephthalate adipic acid and preparation method thereof 东华工程科技股份有限公司 2025-05-13 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-109912470-B Synthetic method of 3- (benzenesulfonyl) propionic acid 苏州华道生物药业股份有限公司 2021-01-05 CN claimed
CN-109912470-A A kind of synthetic method of 3- (benzene sulfonyl) propionic acid 苏州华道生物药业股份有限公司 2019-06-21 CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 WO claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
US-6398857-B1 ACCUSTIC PIEZOELECTRIC; HOT MELT INK JET PRINTING; BENZOIC ACID VEHICLE; ALKYL OR PHENYL CARBOXYLIC ACID VISCOSITY MODIFIER; RETAINS DESIRED HARDNESS XEROX CORPORATION 2002-06-04 US claimed
CN-1227540-A Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity DARWIN DISCOVERY CO LTD (GB) 1999-09-01 CN claimed
WO-1993013076-A1 GASTRIC ACID SECRETION-INHIBITING, AND GASTROCYTOPROTECTIVE PHARMACEUTICAL COMPOSITIONS, NOVEL FAMOTIDINE SALTS AND PROCESS FOR PREPARING SAME Richter Gedeon Vegyészeti Gyár Rt. (HU) 1993-07-08 WO claimed
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 US disclosed
US-12606723-B2 Thermosetting resin composition, semiconductor device and electrical/electronic component KYOCERA CORPORATION (JP) 2026-04-21 US disclosed
US-12551555-B2 Compositions and methods for potentiating immune activity KUMQUAT BIOSCIENCES INC. (US) 2026-02-17 US disclosed
US-4637833-A OIL WELLS, GAS WELLS PHILLIPS PETROLEUM CO. (US) 1987-01-20 US disclosed
US-4400504-A DYEING AND PRINTING CELLULOSE AND POLYAMIDE AND-URETHANE FIBERS; TRIAZINE, PYRIDINE AND PYRIMIDINE DYES BAYER AKTIENGESELLSCHAFT (DE) 1983-08-23 US disclosed
EP-0053743-A2 Reactive dioxazine dyestuffs, process for their preparation and their use in dyeing and printing fibrous materials containing hydroxyle or amide groups BAYER AG (DE) 1982-06-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS HSD11B1 3994/4885HTT 1387/4885NPSR1 3502/4885
US-12551555-B2 Compositions and methods for potentiating immune activity PTPRCAP, PTPN2, PTPRC HSD11B1 4517/4885HTT 2995/4885NPSR1 3475/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS HSD11B1 3994/4885HTT 1387/4885NPSR1 3502/4885
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL HSD11B1 3490/4885HTT 1286/4885NPSR1 2851/4885
US-12606723-B2 Thermosetting resin composition, semiconductor device and electrical/electronic component RPS3A, SEM1, DAP3 HSD11B1 2799/4885HTT 1550/4885NPSR1 3781/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS HSD11B1 3994/4885HTT 1387/4885NPSR1 3502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.