Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MTOR | P42345 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11614619 | 0.88 | MMP13 (0.58) | TSHRMTORNAMPTROCK2ROCK1 | |
| SCHEMBL11612243 | 0.87 | MTOR (0.54) | TSHRMTORNAMPTROCK2ROCK1 | |
| SCHEMBL11613400 | 0.87 | MTOR (0.54) | TSHRMTORNAMPTPOLBROCK2 | |
| SCHEMBL11615157 | 0.87 | MTOR (0.54) | TSHRMTORNAMPTPOLBROCK2 | |
| SCHEMBL11168593 | 0.87 | MTOR (0.71) | MTORNAMPTROCK2ROCK1NPY5R | |
| SCHEMBL11615678 | 0.86 | MTOR (0.53) | TSHRMTORNAMPTPOLBROCK2 | |
| SCHEMBL11614065 | 0.85 | LMNA (0.54) | TSHRMTORNAMPTROCK2ROCK1 | |
| SCHEMBL11616354 | 0.83 | MTOR (0.61) | TSHRMTORNAMPTROCK2ROCK1 | |
| SCHEMBL11617207 | 0.82 | MAPT (0.63) | MTORNAMPTPOLBMEN1KMT2A | |
| SCHEMBL11614038 | 0.82 | ALDH1A1 (0.58) | MTORNAMPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088766-A | PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4001256-A | PROSTAGLANDIN PRODUCTION IN MAMMALS | THE UPJOHN COMPANY (US) | 1977-01-04 | — | — | US | disclosed |