Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11614682 | 0.88 | TSHR (0.54) | RAB9ASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11617264 | 0.87 | KDM4E (0.44) | RAB9ASMN1; SMN2ALDH1A1TNFCNR2 | |
| SCHEMBL11621562 | 0.87 | ALDH1A1 (0.48) | RAB9ASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11617070 | 0.85 | ALDH1A1 (0.42) | RAB9ASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11616243 | 0.85 | RAB9A (0.40) | RAB9ASMN1; SMN2ALDH1A1TNFCNR2 | |
| SCHEMBL11621082 | 0.84 | ALDH1A1 (0.41) | RAB9ASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11613402 | 0.83 | ALDH1A1 (0.42) | RAB9ASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11613405 | 0.83 | ALDH1A1 (0.42) | RAB9ASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11621125 | 0.82 | LMNA (0.54) | RAB9ASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11616351 | 0.77 | TNF (0.41) | ALDH1A1TNFTSHRHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130649-A | Cyclohepta [B]pyridine-2-carboxylic acid derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-12-19 | — | — | US | disclosed |